Objective:

To demonstrate that the sum of the biomarkers of the microcirculation: CO2 delta, baseline, lactate and central ScVO2 are better predictors of mortality than the SOFA scale in septic shock.

Study

Study method:

This study was scheduled to be performed in the ICU of the Hospital of Mexico City in a period from 1 of March 2014 to 1 of July 2017. This is a comparative, ambispective, observational and descriptive.

Once these data were obtained, a score was given for each of the biomarkers based on previous studies and a new titration scale was performed where biomarkers were integrated, which was called «microcirculation biomarkers scale» (EBM) and according to the obtained score was assigned a percentage of mortality which was compared with the mortality of the SOFA scale already predetermined for patients with septic shock. The results obtained from these scales were grouped in Pearson correlation graphs as quantitative variables, in the abscissa axis were placed the days of hospital stay and in the axis of the ordinates the obtained score. Subsequently, an association was made with Pearson scales between the scores obtained in the scales with the percentage of mortality of each of the scales, obtaining a linear correlation in the two scales. However, correlation tables between the SOFA and EBM Scale were made The percentage of mortality in a period of 30 days.

Conclusion:

It was found that the ability to predict death, which is more significant in the SOFA scale is less sensitive and more specific, however, the EMB scale resulted with a sensitivity of 100% to predict death with a specificity of 76%. Therefore, it is considered a valid scale to determine death in the ICU, however, more studies are required to compare the specificity of this scale.

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