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Revista alergia México
versão On-line ISSN 2448-9190
Resumo
BEDOLLA-BARAJAS, Martín et al. Prevalence of vitamin D insufficiency and deficiency in Mexican adults with allergic asthma. Rev. alerg. Méx. [online]. 2017, vol.64, n.2, pp.178-187. ISSN 2448-9190. https://doi.org/10.29262/ram.v64i2.255.
Background:
Hypovitaminosis D has been associated with various chronic diseases such as infections, autoimmune diseases, chronic obstructive pulmonary disease, cancer and asthma
Objective:
The objective at hand is to determine the prevalence of vitamin D (VD) insufficiency and deficiency in adults with allergic asthma.
Methods:
Through a cross-sectional study, we analyzed corresponding data amongst 135 patients.VD concentration was categorized as sufficient (≥ 30 ng/mL), insufficient (21-29 ng/mL), and deficient (≤ 20 ng/mL). The level of VD deficiency was measured through chemo-luminescence. We estimated the prevalence of VD alterations and their respective confidence intervals at 95 % (CI 95 %).
Results:
Within the analyzed population, there were 99/135 women (73.3 %); the mean age was 34.5 ± 10.3 years. The mean concentration of VD was 17.9 ± 6.9 ng/mL and the median was 17 ng/mL. The prevalence of VD insufficiency and deficiency was 25.2 % (CI 95 %, 18.6-33.2 %) and 71.1 % (CI 95 %, 62.9-78.1 %), respectively; VD concentrations ≤ 10 ng/mL had 13.3 % (CI 95 %, 8.5-20.2 %) and ≥ 30 ng/mL at 3.7 % (CI 95 %: 1.4-8.6 %). When we contrasted the men to the women, the median concentration of VD did not differ significantly (16 ng/mL vs. 18 ng/mL, p = 0.71).
Conclusions:
In this study, patients with allergic asthma had distinctively reduced VD concentration levels; future research will determine if and how VD affects the severity of asthma.
Palavras-chave : Vitamin D; Asthma; Adult.