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Medicina interna de México
versão impressa ISSN 0186-4866
Resumo
VERGARA-ORDUNA, Fernando Iván et al. Post- and pre-Valsalva pulse pressure gradient as a marker of left ventricle systolic dysfunction. Med. interna Méx. [online]. 2019, vol.35, n.5, pp.659-668. Epub 30-Abr-2021. ISSN 0186-4866. https://doi.org/10.24245/mim.v35i5.2206.
BACKGROUND:
Heart failure affects to 26 million people worldwide. The variation of the blood pressure and heart rate values after performing the Valsalva maneuver has been evaluated, finding a correlation between left ventricular function and natriuretic atrial peptide.
OBJECTIVE:
To determine if post- and pre-Valsalva pulse pressure gradient is useful as marker of left ventricle systolic dysfunction.
MATERIAL AND METHOD:
A cohort study was done from January 1st to June 30, 2017, determining left ventricular ejection fraction, cerebral natriuretic peptide, as well as the subtraction of post-Valsalva and pre-Valsalva pulse pressure, this variable was determined as pulse pressure gradient.
RESULTS:
There were included 32 patients. A gradient figure of less than 4.22 had a negative correlation with a left ventricular ejection fraction lesser than 50%, with a correlation coefficient of -0.562 and a p value of 0.001, in addition to having an area under the curve of 0.71.
CONCLUSIONS:
The gradient and the ejection fraction had a negative correlation, this in the indeterminate area of the systolic function. An LVEF lesser than 50% implies risk of decompensation and a depressed LVEF.
Palavras-chave : Heart failure; Valsalva maneuver; Left ventricular function; Cerebral natriuretic peptide; Pulse pressure.