OBJECTIVE:

To analyze the Negative Predictive Value of the Sentinel Lymph Node Selective Biopsy Technique in Endometrial Carcinoma.

MATERIALS AND METHODS:

Prospective cohort observational study. Carried out in the General University Hospital of Ciudad Real between 2011 and 2016. Patients diagnosed with endometrial carcinoma with stage I-II, suitable for surgical intervention with uterine cervix accessible for marker injection, were included. Patients with involvement of adjacent or distant organs were excluded. 34 variables were studied, for the statistical analysis the SPSS computer program was used.

RESULTS:

65 patients were included in the study. 59 of the tumors were endometrial carcinoma type 1 and 6 type 2. The rate of identification of sentinel lymph node in the SPECT TAC was 84% and with dual staining (radiocolloid and methylene blue) of 100%. The sentinel lymph node was located in the pelvic region in 60/65 and in the para-aortic region in 5/65 of the cases, whose most frequent lymph node territory was the lymph nodes adjacent to the external iliac vessels. No cases of metastasis in non-sentinel lymph nodes were detected. The bilaterality rate was 9.2%. The tumor recurrence rate was 3%, with a 5-year survival of 96.9%.

CONCLUSIONS:

The Negative Predictive Value of the technique was 100%, it is a good alternative to lymphadenectomy. We recommend dual staining injected into the cervix to achieve greater localization of sentinel lymph node.