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Gaceta médica de México
versão On-line ISSN 2696-1288versão impressa ISSN 0016-3813
Resumo
MORALES-MONTALVO, Susana I. et al. Infrared thermography for normal endothelial function screening. Gac. Méd. Méx [online]. 2024, vol.160, n.1, pp.26-35. Epub 26-Mar-2024. ISSN 2696-1288. https://doi.org/10.24875/gmm.23000293.
Background:
Endothelial dysfunction (ED) suspicion will allow to prevent accelerated atherosclerosis and premature death.
Objective:
To establish the usefulness of thermography for endothelial function screening in adults with cardiovascular risk factors.
Material and methods:
Cross-sectional, analytical diagnostic test. A brachial arterial diameter (BAD) increase <11 % at one-minute post-ischemia meant probable ED and was confirmed if BAD was ≥ 11 % post-sublingual nitroglycerin. Thermographic photographs of the palmar region were obtained at one minute. Descriptive statistics, ROC curve, Mann-Whitneys U-test, chi-square test, or Fishers exact test were used.
Results:
Thirty-eight subjects with a median age of 50 years, and with 624 thermographic measurements were included. Nine had ED (flow-mediated vasodilation (FMV): 2.5 %. The best cutoff point for normal endothelial function in subjects with cardiovascular risk factors was ≥ 36 °C at one minute of ischemia, with 85 % sensitivity, 70 % specificity, positive and negative predictive values of 78 and 77 %, area under the curve of 0.796, LR+ 2.82, LR- 0.22.
Conclusions:
An infrared thermography-measured temperature in the palmar region greater than or equal to 36 °C after one minute of ischemia is practical, non-invasive, and inexpensive for normal endothelial function screening in adults with cardiovascular risk factors.
Palavras-chave : Atherosclerosis; Vascular endothelium; Thermography; Vasodilation.