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Medicina interna de México
versão impressa ISSN 0186-4866
Resumo
RIVAS-SALAZAR, Rommel Jesús; BALTAZAR-TORRES, José Ángel e CENTURION-MORA, Saily Guadalupe. Fulminant hepatic failure due to paracetamol. Med. interna Méx. [online]. 2019, vol.35, n.5, pp.789-794. Epub 30-Abr-2021. ISSN 0186-4866. https://doi.org/10.24245/mim.v35i5.2519.
Acute liver failure is a rare disease but life-threatening, and occurs more frequently in patients without preexisting liver disease. Paracetamol (acetaminophen) is one of the analgesic-antipyretic drugs most frequently prescribed by physicians and self- medicated by people, whose adverse effects are mild discomfort and even lethal side effects that do not necessarily require the toxic dose to cause such serious effects. Not surprisingly, acetaminophen remains a major cause of overdose: from intentional poisoning (suicide) and unintentional (chronic use), whose major effects are ranging from fulminant hepatic failure related to overdose to death; half of these episodes are attributable to paracetamol, and these cases seem to be increasing more and more, because of its easy access and free sale. The aim of this paper is to present a case report and a literature review.
Palavras-chave : Acute liver failure; Fulminant hepatic failure; Paracetamol; Acetaminophen.