Resumo

CASTILLA PEON, María Fernanda. Endocrinologic disorders in pediatric cancer survivors. Bol. Med. Hosp. Infant. Mex. [online]. 2014, vol.71, n.3, pp.180-187. ISSN 1665-1146.

Advances in treatment of childhood cancer have increased the rate of cure and survival in these patients. It is believed that in the near future 1/1,000 inhabitants <25 years of age will be a cancer survivor. Because of this, it is necessary to improve health care in this population, with endocrinologic disorders being one of the affected systems needing special attention. Both the neoplasm and its treatment including radiotherapy, chemotherapy and ablative procedures may injure endocrine system-related structures. Growth disorders are frequent in these patients so are primary or secondary thyroid disorders, sexual and reproductive dysfunction, bone health problems and increased cardiovascular risk. Endocrinologic side effects may present in the short term or >10 years after conclusion of treatment. In this paper we propose a guideline for surveillance and timely referral to a specialist for these patients.

Palavras-chave : Endocrine system; Neoplasms; Adverse effects; Chemotherapy; Radiotherapy; Children.