Resumo

ARTEAGA-CRESPO, Yasiel; CARBALLO-ABREU, Leila Rosa; TACORONTE-MORALES, Juan Enrique  e  NUNEZ-FIGUEREDO, Yanier. Neuroprotective and neuroregenerative action of salts of isolated resin acids of conifers rosin from western Cuba. Rev. Chapingo ser. cienc. for. ambient [online]. 2012, vol.18, n.1, pp.135-142. ISSN 2007-4018.  https://doi.org/10.5154/r.rchscfa.2010.10.092.

Neuropsychiatric diseases affect more than 10 % of the Cuban population and 25 % worldwide. Most drugs used to treat central nervous system disorders are expensive and create severe side reactions. Efforts are currently being developed for the implementation of secondary metabolites such as environmentally sustainable sources for the treatment of nervous system diseases, including stroke and other Parkinson's-type neuropathologies, and Huntington's motor disorders, enabling an effective neuroprotection as well as short periods of neuroregeneration time with minimal sequels. The objective was to evaluate the neuroprotective and neuroregenerative action of sodium salts of isolated resin acids from Cuban conifers. The study results suggest that the sodium salt of resin acids can be used as a structural bioisosteric isoanalogue precursor with specific therapeutic actions such as neuroregeneration and neuroprotection in the treatment of ischemic diseases.

Palavras-chave : Rosin; central nervous system; neuropathologies; neuroprotection; neuroregeneration.