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Gaceta mexicana de oncología
versão On-line ISSN 2565-005Xversão impressa ISSN 1665-9201
Resumo
CORTES-ESTEBAN, Patricia et al. High-grade serous epithelial ovarian cancer, BRCA negative, in two 18-year-old women: case report. Gac. mex. oncol. [online]. 2023, vol.22, suppl.1, pp.41-46. Epub 11-Set-2023. ISSN 2565-005X. https://doi.org/10.24875/j.gamo.220000951.
Two previously healthy 18-year-old Mexican women referred for medical evaluation due to ascites. Clinical studies revealed the presence of ovarian-dependent tumors, and elevated CA-125. A diagnostic laparotomy was performed, with a pathology report of a high-grade papillary serous adenocarcinoma. BRCA 1 and 2 was performed and reported negative for both patients. Chemotherapy and antiangiogenic treatment were started. One of the patients was considered a candidate for a poly (ADP-ribose) polymerase inhibitor.
Palavras-chave : Ovarian cancer; BRCA; PARP inhibitor.